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Endocrine Consequences of Breast Cancer Therapy and Survivorship

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Key Points

  • Approximately 1 in 8 women will be diagnosed with invasive breast cancer in their lifetime, with the incidence rising due to improved screening
  • The majority of breast cancers express oestrogen and/or progesterone receptors, in which case endocrine therapies such as tamoxifen and aromatase inhibitors reduce the risk of breast cancer recurrence and improve survival
  • Many breast cancer treatments, especially for hormone-positive breast cancer, reduce oestrogen production or effect
  • This can cause early menopause, menopausal symptoms, bone health implications, increased cardiovascular risks, and fertility and pregnancy considerations
  • With 5-year survival rates of breast cancer in Australia of 92%, clinicians should ensure they are well informed about survivorship care of these women
Dr Meg Henze

Dr Meg Henze is a highly regarded Perth endocrinologist who manages a wide range of diabetes and endocrine disorders. Meg is a Consultant Endocrinologist at Sir Charles Gairdner Hospital and treats private patients at her Nedlands clinic in addition to her regional clinics in Geraldton and Albany. She completed her Medical degree with Honours in 2009 from the University of Western Australia. Post-graduation, Meg had exposure in a broad range of specialties and completed a diploma in Obstetrics and Gynaecology in 2012. She commenced physician training and after successfully passing the basic training examinations of the Royal Australasian College of Physicians (RACP) in 2014, she progressed into advanced training in Endocrinology and was awarded Fellowship of the RACP in 2017. Meg’s advanced endocrine training was undertaken at Fiona Stanley Hospital, Sir Charles Gairdner Hospital and King Edward Memorial Hospital.